TTA-A2
Cat. No. :YN360270
CAS No. :953778-63-7
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order@ubiochem.com| Product Name: | TTA-A2 |
| CAS NO.: | 953778-63-7 |
| Chemical Name: | |
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| Molecular Weight: | 378.39 |
| Molecular Formula: | C₂₀H₂₁F₃N₂O₂ |
| SMILES: | O=C(N[C@@H](C1=NC=C(OCC(F)(F)F)C=C1)C)CC2=CC=C(C3CC3)C=C2 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | TTA-A2 is a potent, selective and orally activet-type voltage gated calcium channelantagonist with reduced pregnane X receptor (PXR) activation. TTA-A2 is equally potent against the Cav3.1 (a1G) and Cav3.2 (a1H) channels with IC50 values of 89nM and 92nM, respectively, at -80 and -100 mV holding potentials. TTA-A2 can be used for the research of a variety of human neurological diseases, including sleep disorders and epilepsy. |
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