CAY10404
Cat. No. :YN330179
CAS No. :340267-36-9
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order@ubiochem.com| Product Name: | CAY10404 |
| CAS NO.: | 340267-36-9 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 367.34 |
| Molecular Formula: | C₁₇H₁₂F₃NO₃S |
| SMILES: | FC(C1=C(C2=CC=CC=C2)C(C3=CC=C(S(=O)(C)=O)C=C3)=NO1)(F)F |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | CAY10404 is a potent and highly selectivecyclooxygenase-2 (COX-2)inhibitor with an IC50 of 1nM. CAY10404 exhibits no inhibition of COX-1 (IC50>500 µM). CAY10404 is a potent inhibitor ofPKB/Akt and MAPKsignaling pathways and inducesapoptosisin NSCLC cells. CAY10404, a diarylisoxazole, has good analgesic, anti-inflammatory, and anti-cancer activities . |
| IC50&Target: | |
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