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AKOS-22

Cat. No. :YN360260

  • CAS No. :878983-38-1

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    • Product Name:AKOS-22
      CAS NO.:878983-38-1
      Chemical Name:
      Synonyms:
      Molecular Weight:467.87
      Molecular Formula:C₂₂H₂₁ClF₃N₃O₃
      SMILES:O=C(C(N1CCC(NC2=CC=C(OC(F)(F)F)C=C2)CC1)C3)N(C4=CC=C(Cl)C=C4)C3=O
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:AKOS-22 is a potent mitochondrial proteinVDAC1(voltage-dependent anion channel 1) inhibitor (Kd=15.4μM). AKOS-22 interacts with VDAC1 and inhibiting both VDAC1 oligomerization and apoptosis. AKOS-22 protects against mitochondrial dysfunction.
      IC50&Target:
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      Clinical Trial:
      Solvent & Solubility:
      References:
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