TC-I 2014
Cat. No. :YN360248
CAS No. :1221349-53-6
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5mg
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Product Name: | TC-I 2014 |
CAS NO.: | 1221349-53-6 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 467.41 |
Molecular Formula: | C₂₃H₁₉F₆N₃O |
SMILES: | FC(C1=CC=CC=C1C2=CC(C(F)(F)F)=C3C(N=C(C4=NOC5(CCCCC5)C4)N3)=C2)(F)F |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | TC-I 2014 (compound 5) is a potent and orally active Benzimidazole-containingtransient receptor potential melastatin 8 (TRPM8)antagonist, with IC50 values of 0.8nM, 3.0nM and 4.4nM for canine, human and rat channels respectively. TC-I 2014 exhibits antiallodynic properties in pain models. |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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