BPN-15606
Cat. No. :YN380055
CAS No. :1914989-49-3
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order@ubiochem.com| Product Name: | BPN-15606 |
| CAS NO.: | 1914989-49-3 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 418.47 |
| Molecular Formula: | C₂₃H₂₃FN₆O |
| SMILES: | CC1=CC(C2=NC(OC)=C(N3C=C(C)N=C3)C=C2)=NN=C1N[C@H](C4=CC=C(F)C=C4)C |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | BPN-15606 is a highly potent, orally activeγ-secretasemodulator (GSM), attenuates the production ofAβ42 and Aβ40by SHSY5Y neuroblastoma cells with IC50 values of 7nM and 17nM, respectively. BPN-15606 lowers Aβ42 and Aβ40 levels in the central nervous system of rats and mice. BPN-15606 has acceptable PK/PD properties, including bioavailability, half-life, and clearance. |
| IC50&Target: | |
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