DSR-141562
Cat. No. :YN371754
CAS No. :2007975-22-4
86-020-82000279
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order@ubiochem.com| Product Name: | DSR-141562 |
| CAS NO.: | 2007975-22-4 |
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| Molecular Weight: | 414.42 |
| Molecular Formula: | C₁₉H₂₅F₃N₄O₃ |
| SMILES: | O=C1N(C)C(OC[C@H]2CC[C@H](C(F)(F)F)CC2)=NN3C1=CN=C3C4CCOCC4 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | DSR-141562 is a novel, orally active, and selective brain-penetrantphosphodiesterase 1 (PDE1)inhibitor. DSR-141562 shows preferential selectivity for human PDE1B with an IC50 of 43.9nM, and theIC50 values for human PDE1A and 1C are 97.6 and 431.8nM, respectively. DSR-141562 can be used for the study of positive symptoms, negative symptoms and cognitive impairments associated with schizophrenia. |
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