AZD7325
Cat. No. :YN360256
CAS No. :942437-37-8
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order@ubiochem.com| Product Name: | AZD7325 |
| CAS NO.: | 942437-37-8 |
| Chemical Name: | |
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| Molecular Weight: | 354.38 |
| Molecular Formula: | C₁₉H₁₉FN₄O₂ |
| SMILES: | O=C(C1=NN=C2C(C3=C(OC)C=CC=C3F)=CC=CC2=C1N)NCCC |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | AZD7325 is a potent and orally active partial selective PAM ofGABAAα2 and Aα3 receptor(Ki=0.3 and 1.3nM, respectively), and has less antagonistic efficacy at the Aα1 and Aα5 receptor subtypes . AZD7325 is a moderateCYP1A2 and a potentCYP3A4inducer in vitro. AZD7325 has the potential for the investigation of anxiety and dravet syndrome. PAM: positive allosteric modulator. |
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