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GFB-8438

Cat. No. :YN360417

  • CAS No. :2304549-73-1

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    • Product Name:GFB-8438
      CAS NO.:2304549-73-1
      Chemical Name:
      Synonyms:
      Molecular Weight:386.76
      Molecular Formula:C₁₆H₁₄ClF₃N₄O₂
      SMILES:O=C1CN(C2=C(Cl)C(NN=C2)=O)CCN1CC3=CC=CC=C3C(F)(F)F
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:GFB-8438 is a novel, potent, and subtype selective TRP channel subfamily C (TRPC) inhibitor that is equipotent against TRPC4 and TRPC5 with IC50 of 0.18 μM and 0.29 μM, and shows excellent selectivity against TRPC6, other TRP family members , NaV 1.5, as well as limited activity against the hERG channel.
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