GFB-8438
Cat. No. :YN360417
CAS No. :2304549-73-1
Product Name: | GFB-8438 |
CAS NO.: | 2304549-73-1 |
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Molecular Weight: | 386.76 |
Molecular Formula: | C₁₆H₁₄ClF₃N₄O₂ |
SMILES: | O=C1CN(C2=C(Cl)C(NN=C2)=O)CCN1CC3=CC=CC=C3C(F)(F)F |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | GFB-8438 is a novel, potent, and subtype selective TRP channel subfamily C (TRPC) inhibitor that is equipotent against TRPC4 and TRPC5 with IC50 of 0.18 μM and 0.29 μM, and shows excellent selectivity against TRPC6, other TRP family members , NaV 1.5, as well as limited activity against the hERG channel. |
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