nAChR agonist CMPI hydrochloride
Cat. No. :YN360445
CAS No. :2250025-94-4
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order@ubiochem.com| Product Name: | nAChR agonist CMPI hydrochloride |
| CAS NO.: | 2250025-94-4 |
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| Molecular Weight: | 379.28 |
| Molecular Formula: | C₁₈H₂₀Cl₂N₄O |
| SMILES: | CC1=C(C2=CC(C3=CC=CC=C3Cl)=NO2)C=NN1C4CCNCC4.[H]Cl |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | nAChR agonist CMPI hydrochloride is a potent and selective positive allosteric modulator (PAM) ofnAChRcontaining a α4:α4 subunit interface. nAChR agonist CMPI hydrochloride enhances the response of(α4)3(β2)2nAChRto ACh (10 µM) with an EC50 of 0.26 µM. nAChR agonist CMPI hydrochloride has potential for the research of nicotine dependence and many neuropsychiatric conditions associated with decreased brain cholinergic activity. |
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