Penitrem A
Cat. No. :YN361004
CAS No. :12627-35-9
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order@ubiochem.com| Product Name: | Penitrem A |
| CAS NO.: | 12627-35-9 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 634.20 |
| Molecular Formula: | C₃₇H₄₄ClNO₆ |
| SMILES: | O[C@]12[C@]34[C@@H]([C@H]([C@@H](C(C)=C)O[C@@]4([H])CC[C@@]1([C@]5(C(N6)=C7[C@](OC(C)([C@]8([H])[C@@]([C@]9([H])C8)(O)C%10=C7C6=CC(Cl)=C%10CC9=C)C)([H])[C@]5([H])CC2)C)C)O)O3 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Penitrem A is an indole diterpene neurotoxic alkaloid produced byPenicillium, acts as a selectiveBK channelantagonist with antiproliferative and anti-invasive activities against multiple malignancies. Penitrem A increases the spontaneous release of endogenous glutamate, gamma-aminobutyric acid (GABA) and aspartate from cerebrocortical synaptosomes, and induces tremorgenic syndromes in animals. |
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| References: |
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