TAN-452
Cat. No. :YN320766
CAS No. :892039-23-5
Pack size
price
inventory
5mg
Enquiry
Enquiry
10mg
Enquiry
Enquiry
25mg
Enquiry
Enquiry
50mg
Enquiry
Enquiry
86-020-82000279
sales@ubiochem.com
order@ubiochem.com| Product Name: | TAN-452 |
| CAS NO.: | 892039-23-5 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 486.56 |
| Molecular Formula: | C₂₉H₃₀N₂O₅ |
| SMILES: | O=C(C1=CC2=C(C=C1)C3=C([C@@](OC4=C(O)C=CC(C5)=C46)([H])[C@]76[C@@]([C@]5([H])N(CC8CC8)CC7)(O)C3)N2)OCC |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | TAN-452 is an orally active, selective peripherally actingδ-opioid receptor (DOR)antagonist with a Ki of 0.47 nM and aKbof 0.21 nM. TAN-452 is an antagonist forμ-opioid receptor(MOR;Ki=36.56 nM and Kb=9.43 nM) and κ-opioid receptor(KOR;Ki=5.31 nM and Kb=7.18 nM). TAN-452, a derivative of Naltrindole, demonstrates low brain penetrability and attenuates morphine-induced side effects without affecting pain control. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
TELL : +86-020-82000279
Add:Room 519, Block F, Guangzhou International Business Incubator, No.3 Lanyue Road, Science Town, Huangpu District, Guangzhou, China.
