Huwentoxin-IV
Cat. No. :YN361040
CAS No. :526224-73-7
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order@ubiochem.com| Product Name: | Huwentoxin-IV |
| CAS NO.: | 526224-73-7 |
| Chemical Name: | |
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| Molecular Weight: | 4106.78 |
| Molecular Formula: | C₁₇₄H₂₇₈N₅₂O₅₁S₆ |
| SMILES: | 无SMILES |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Huwentoxin-IV is a potent and selectivesodium channelblocker, inhibits neuronalNav1.7,Nav1.2,Nav1.3 and Nav1.4with IC50s of 26, 150, 338 and 400nM, respectively. Huwentoxin-IV preferentially blocks peripheral nerve subtype Nav1.7 by binding neurotoxin receptor site 4. Huwentoxin-IV has analgesic effects on animal models of inflammatory and neuropathic pain. |
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