Ro 90-7501
Cat. No. :YN370262
CAS No. :293762-45-5
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order@ubiochem.com| Product Name: | Ro 90-7501 |
| CAS NO.: | 293762-45-5 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 340.38 |
| Molecular Formula: | C₂₀H₁₆N₆ |
| SMILES: | NC1=CC=C2C(N=C(C3=CC=C4C(N=C(C5=CC=C(N)C=C5)N4)=C3)N2)=C1 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Ro 90-7501 is anamyloid β42(Aβ42) fibril assemblyinhibitor that reducesAβ42-induced cytotoxicity (EC50of 2μM). Ro 90-7501 inhibitsATMphosphorylation and DNA repair. RO 90-7501 selectively enhances toll-like receptor 3 (TLR3) and RIG-I-like receptor (RLR) lig and -induced IFN-β gene expression and antiviral response. Ro 90-7501 also inhibitsprotein phosphatase 5 (PP5)in a TPR-dependent manner. Ro 90-7501 has significant radiosensitizing effects on cervical cancer cells. |
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