L-745870 trihydrochloride
Cat. No. :YN1730064
CAS No. :866021-03-6
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order@ubiochem.com| Product Name: | L-745870 trihydrochloride |
| CAS NO.: | 866021-03-6 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 436.21 |
| Molecular Formula: | C₁₈H₂₂Cl₄N₄ |
| SMILES: | ClC(C=C1)=CC=C1N(CC2)CCN2CC3=CNC4=NC=CC=C43.Cl.Cl.Cl |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | L-745870 trihydrochloride is a potent, selective, brain-penetrant and orally activedopamine D4receptorantagonist with aKiof 0.43nM. L-745870 trihydrochloride shows weaker affinity for D2(Kiof 960nM) and D3(Kiof 2300nM) receptors, and exhibits moderate affinity for 5-HT2receptors, sigma sites and α-adrenoceptors . |
| IC50&Target: | |
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| Solvent & Solubility: | |
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