SNAP 94847 hydrochloride
Cat. No. :YN320330
CAS No. :1781934-47-1
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Product Name: | SNAP 94847 hydrochloride |
CAS NO.: | 1781934-47-1 |
Chemical Name: | |
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Molecular Weight: | 515.03 |
Molecular Formula: | C₂₉H₃₃ClF₂N₂O₂ |
SMILES: | Cl[H].FC1=CC(OC(C=C2)=CC=C2CN3CCC(CC3)C4=CC(NC(C(C)C)=O)=CC=C4C)=CC=C1F |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | SNAP 94847 hydrochloride is a novel, high affinity selectivemelanin-concentrating hormonereceptor1 (MCHR1)antagonist with (Ki= 2.2nM,Kd=530 pM), it displays >80-fold and >500-fold selectivity overMCHα1A and MCHD2receptors respectively. SNAP 94847 hydrochloride binds with high affinity to the mouse and rat MCHR1 with minimal cross-reactivity to other GPCR, ion channels, enzymes, and transporters. |
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