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Jatrorrhizine hydroxide

Cat. No. :YN321732

  • CAS No. :483-43-2

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    • Product Name:Jatrorrhizine hydroxide
      CAS NO.:483-43-2
      Chemical Name:
      Synonyms:
      Molecular Weight:355.38
      Molecular Formula:C₂₀H₂₁NO₅
      SMILES:COC1=C(OC)C2=C[N+]3=C(C4=CC(OC)=C(O)C=C4CC3)C=C2C=C1.[OH-]
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:Jatrorrhizine hydroxide is an alkaloid isolated fromCoptis chinensiswith neuroprotective, antimicrobial, antiplasmodial and antioxidant activities. Jatrorrhizine hydroxide is a potent and orally active inhibitor ofAChE(IC50=872nM) over >115-fold selectivity for BuChE. Jatrorrhizine hydroxide reduces uptake ofserotonin (5-HT) and norepinephrine (NE)via inhibition of uptake-2 transporters.
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