Kaurenoic acid
Cat. No. :YN482684
CAS No. :6730-83-2
Product Name: | Kaurenoic acid |
CAS NO.: | 6730-83-2 |
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Molecular Weight: | 302.45 |
Molecular Formula: | C₂₀H₃₀O₂ |
SMILES: | C[C@@]1(C(O)=O)CCC[C@@]2(C)[C@@]3([H])[C@@]4(CC([C@H](CC3)C4)=C)CC[C@]12[H] |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Kaurenoic acid has cytotoxic and embryotoxic effects. Kaurenoic acid has anti-inflammatory potential in acetic acid-induced colitis, decreases in MDA level, an indicator of lipoperoxidation in colon tissue. Kaurenoic acid exerts a uterine relaxant effect acting principally through calcium blockade and in part, by the opening of ATP-sensitive potassium channels. Kaurenoic acid exhibits an analgesic effect in a consistent manner and that its mechanisms involve the inhibition of cytokine production and activation of the NO-cyclic GMP-protein kinase G-ATP-sensitive potassium channel signaling pathway. Kaurenoic acid derivatives has antimicrobial activity of substituted on carbon-15 at concentrations greater than or equal to 250 micrograms/ml. Kaurenoic acid has inhibitory effects on LPS-induced inflammatory response in RAW264.7 macrophages. |
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