Chemical structure
Cat.No.
Product Name
CAS no.
Target
YN440147 CSF1R-IN-2 2271119-26-5
CSF1R-IN-2 (compound 5) is an oral-active inhibitor ofSRC,MET and c-FMS, with IC50 values of 0.12nM, 0.14nM and 0.76nM for SRC, MET and c-FMS respectively.
Pexidartinib (PLX3397) is an oral, potent mutil-targeted receptor tyrosine kinase inhibitor of CSF-1R, Kit, and Flt3 with IC50 of 20 nM, 10 nM and 160 nM, respectively. Phase 3.
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