Chemical structure
Cat.No.
Product Name
CAS no.
Target
YN440167 SRI 31215 TFA 1832686-44-8
SRI 31215 (TFA), a triplex inhibitor ofmatriptase,hepsin and hepatocyte growth factor activator (HGFA)with IC50s of 0.69μM, 0.65μM, 0.3μM, blocks pro-HGF activation and thus mimics the activity of HAI-1/2.
Capmatinib (INCB28060) is a novel, ATP-competitive inhibitor of c-MET with IC50 of 0.13 nM in a cell-free assay, inactive against RONβ, as well as EGFR and HER-3. Phase 1.
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