YN321729 Harmine

Harmine is an alkaloid of the β-carboline family that regulates PPARγ expression through inhibition of the Wnt signaling pathway. It also selectively binds to MAO-A and reversibly inhibits monoamine oxidase A (MAO-A) but n...

YN340183 WHI-P180 211555-08-7

WHI-P180 is a multi-kinase inhibitor with IC50 values of 4.5 and 66 nM for the human proto-oncogene RET and kinase insert domain receptor (KDR) , respectively.

YN321728 Harmine hydrochloride 343-27-1

Harmine, a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds, is a highly cell-permeant and competitive inhibitor of ATP binding to the kinase pocket of DYRK1A, with about 60-fold higher IC50 value ...

YN321729 Harmine 442-51-3

Harmine is an alkaloid of the β-carboline family that regulates PPARγ expression through inhibition of the Wnt signaling pathway. It also selectively binds to MAO-A and reversibly inhibits monoamine oxidase A (MAO-A) but n...

YN350183 Longdaysin 1353867-91-0

Longdaysin is a Casein Kinase inhibitor with IC50 values of 8.8 μM, 5.6 μM, 52 μM and 29 μM for CKIδ, CKIα, ERK2 and CDK7.

YN250033 NH125 278603-08-0

NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.

YN320410 Risperidone 106266-06-2

Risperidone is a mutil-targeted antagonist for dopamine, serotonin, adrenergic and histamine receptors, used to treat schizophrenia and bipolar disorder.

YN320455 Syk Inhibitor II 726695-51-8

Syk Inhibitor II is a potent, high selective and ATP-competitiveSykinhibitor with an IC50 of 41nM. Syk Inhibitor II inhibits5-HTrelease from RBL-cells with an IC50 of 460nM. Syk Inhibitor II shows less potent ag...

YN373130 Wedelolactone 524-12-9

Wedelolactone inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.

YN320432 L 888607 860033-06-3

L 888607 is a potent, and selectiveCRTH2(also known as DP2) agonist with a Ki of 0.8nM.

YN321610 Pimethixene maleate 13187-06-9

Pimethixene (Pimetixene) maleate, an antihistamine, anntimigraine agent and antiserotonergic compound, is a highly potent antagonist of a broad range of monoamine receptors, including a variety of serotonin receptors. Pimet...

YN321065 Treprostinil sodium 289480-64-4

Treprostinil sodium (UT-15, Remodulin, Orenitram, Tyvaso, Trevyent) is a potent agonist of DP1, EP2 and IP receptors with Ki 4.4 nM, 3.6 nM and 32 nM, respectively.

YN320046 Treprostinil 81846-19-7

Treprostinil (LRX-15) is a potent DP1 and EP2 agonist with EC50 values of 0.6±0.1 and 6.2±1.2nM, respectively.

YN321278 Laropiprant 571170-77-9

Laropiprant is a potent, selectiveDP receptorantagonist with Ki values of 0.57nM and 2.95nM for DP receptor and TP Receptor, respectively.

YN320674 Pimozide 2062-78-4

Pimozide is an antipsychotic drug of the diphenylbutylpiperidine class, which is a strong inhibitor of CYP2D6.