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Sennidin A, isolated from the leaves ofCassia angustifolia, inhibitsHCV NS3 helicase, with an IC50 of 0.8μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimul...
Sennidin B, a stereoisomer isolated from the leaves ofCassia angustifolia, has lower activity than Sennidin A. Sennidin A inhibitsHCV NS3 helicase, with an IC50 of 0.8μM. Sennidin A induces phosphorylation of Akt and gl...
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