YN371783 Tamoxifen Citrate 54965-24-1

Tamoxifen Citrate is an antagonist of the estrogen receptor by competitive inhibition of estrogen binding.

YN373233 Cucurbitacin D 3877-86-9

Cucurbitacin D is an active component inCucurbita texana, disrupts interactions betweenHsp90 and two co-chaperones, Cdc37 and p23. Cucurbitacin D prevents Hsp90 client (Her2, Raf, Cdk6, pAkt) maturation without induction of t...

YN330482 Ethoxyquin 91-53-2

Ethoxyquin is an antioxidant used as a food preservative.

YN371784 Tamoxifen 10540-29-1

Tamoxifen is an antagonist of the estrogen receptor in breast tissue.

YN370231 Retaspimycin Hydrochloride 857402-63-2

Retaspimycin Hydrochloride is a potent and water-soluble inhibitor ofHsp90with EC50s of 119nM for both Hsp90 and Grp9.

YN372271 Geldanamycin 30562-34-6

Geldanamycin is a natural existing HSP90 inhibitor with Kd of 1.2 μM, specifically disrupts glucocorticoid receptor (GR)/HSP association.

YN370232 Tanespimycin 75747-14-7

Tanespimycin (17-AAG) is a potent HSP90 inhibitor with IC50 of 5 nM in a cell-free assay, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells. Phase 2.

YN360958 Dihydroberberine 483-15-8

Dihydroberberine inhibitshuman ether-a-go-go-related gene (hERG)channels and remarkably reducesheat shock protein 90 (Hsp90)expression and its interaction with hERG. Dihydroberberine has anti-inflammatory, anti-atherosclerotic,...