YN320521 LY2794193 2173037-97-1

LY2794193 is a highly potent and selectivemGlu3 receptoragonist (hmGlu3Ki=0.927nM，EC50=0.47nM;hmGlu2Ki=412nM，EC50=47.5nM).

YN320383 VU0650786 1809085-30-0

VU0650786 is a potent and selective CNS penetrant negative allosteric modulator ofmetabotropic glutamate receptor subtype 3 (mGlu3 NAM), with an IC50 of 392nM. VU0650786 has antidepressant and anxiolytic activity in rodent...

YN321300 LY341495 201943-63-7

LY341495 is ametabotropic glutamate receptor (mGluR)antagonist with IC50s of 21nM, 14nM, 7.8μM, 8.2μM, 170nM, 990nM, 22μM for mGlu2, mGlu3, mGlu1a, mGlu5a, mGlu8, mGlu7, and mGlu4 receptors, respectively..