YN350251 Isoliquiritin apioside 120926-46-7

Isoliquiritin apioside, a component isolated fromGlycyrrhizae radix rhizome, significantly decreases PMA-induced increases inMMP9activities and suppresses PMA-induced activation ofMAPK and NF-κB. Isoliquiritin apioside...

YN350224 Esculin 531-75-9

Esculin is a glucoside found in horse chestnuts.

YN350249 Dihydrocaffeic acid 1078-61-1

Dihydrocaffeic acid is a phenolic acid found inGynura bicolor, reduces phosphorylation ofMAPK p38 and prevent UVB-induced skin damage. Antioxidant potential and anti-inflammatory activity.

YN350124 p38 MAPK-IN-1 1006378-90-0

p38 MAPK-IN-1 (Compound 4) is a novel potent and selective inhibitor ofp38 MAPKwith IC50 of 68nM. p38 MAPK-IN-1 shows sustained levels, low clearance and good bioavailability.

YN350244 Rotundic acid 20137-37-5

Rotundic acid, a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), and colon cancer (HT-29) cell lines.