YN350025 SB 202190 152121-30-7

SB202190 (FHPI) is a potent p38 MAPK inhibitor targeting p38α/β with IC50 of 50 nM/100 nM in cell-free assays, sometimes used instead of SB 203580 to investigate potential roles for SAPK2a/p38 in vivo.

YN350023 SB 203580 152121-47-6

SB203580 is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM in THP-1 cells, 10-fold less sensitive to SAPK3(106T) and SAPK4(106T) and blocks PKB phosphorylation with IC50 of 3-5 μM.

YN350024 SB 203580 hydrochloride 869185-85-3

SB 203580 hydrochloride (RWJ 64809 hydrochloride) is a selective and ATP-competitivep38 MAPKinhibitor with IC50s of 50nM and 500nM forSAPK2a/p38 and SAPK2b/p38β2, respectively. SB 203580 hydrochloride inhibits...