YN310146 PARP14 inhibitor H10 2084811-68-5

PARP14 inhibitor H10, compound H 10, is a selective inhibitor againstPARP14(IC50=490nM), over other PARPs (≈24 fold over PARP1). PARP14 inhibitor H10 induces caspase-3/7-mediated cellapoptosis.

YN310099 GeA-69 2143475-98-1

GeA-69 is a cell-permeable, selective allosteric inhibitor targeting macrodomain 2 (MD2) of poly-adenosine-diphosphate-ribose polymerase 14 (PARP14) with Kd of 860 nM.