YN340201 LFM-A13

LFM-A13 is a specific Bruton's tyrosine kinase (BTK) inhibitor with IC50 of 2.5 μM, >100-fold selectivity over other protein kinases including JAK1, JAK2, HCK, EGFR,and IRK.

YN340201 LFM-A13 244240-24-2

LFM-A13 is a specific Bruton's tyrosine kinase (BTK) inhibitor with IC50 of 2.5 μM, >100-fold selectivity over other protein kinases including JAK1, JAK2, HCK, EGFR,and IRK.

YN320056 VU0364770 61350-00-3

VU0364770 is a selective and potent positive allosteric modulator (PAM) ofmGlu4. VU0346770 exhibitsEC50s of 290nM and 1.1μM atrat mGlu4 and human mGlu4 receptor, respectively. VU0364770 exhibits antagonist activity at m...

YN372214 Retinoic acid 302-79-4

Tretinoin, which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells.

YN321199 Eglumegad 176199-48-7

Eglumegad (LY354740) is a highly potent and selectivegroup II (mGlu2/3) receptoragonist with IC50s of 5 and 24nM on transfected human mGlu2 and mGlu3 receptors, respectively.

YN330458 Fenofibric acid 42017-89-0

Fenofibric acid is a fibrate that acts as a lipid-lowering agent, decreasing low-density lipoprotein cholesterol and triglycerides.

YN373277 Palmitelaidic Acid 10030-73-6

Palmitelaidic Acid (9-trans-Hexadecenoic acid) is the trans isomer of palmitoleic acid. Palmitoleic acid is one of the most abundant fatty acids in serum and tissue.

YN320375 Anandamide 94421-68-8

An and amide is an immune modulator in the central nervous system acts via not onlycannabinoid receptors(CB1 and CB2) but also other targets (e.g.,GPR18/GPR55).

YN321419 Tranilast 53902-12-8

Tranilast?is an antiallergic drug by inhibiting lipid mediator and cytokine release from inflammatory cells, used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.

YN360934 Ophiopogonin D 945619-74-9

Ophiopogonin D, isolated from the tubers ofOphiopogon japonicus, is a rare naturally occurring C29steroidal glycoside. Ophiopogonin D is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocatio...