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产品结构

货号

产品名称

CAS号

  • YN360257 GSK1702934A 924377-85-5

    GSK1702934A is a selectiveTRPC3agonist. GSK1702934A modulates cardiac contractility and f arrhythmogenesis by activation of TRPC3.

  • YN320580 MCP110 521310-51-0

    MCP110 is an inhibitor of Ras/Raf-1 interaction. MCP110 disrupts the interaction of activated Ras with Raf and is potential for the treatment of human tumors.

  • YN310256 UPF 1069 1048371-03-4

    UPF 1069 is a selective PARP2 inhibitor with IC50 of 0.3 μM. It is ~27-fold selective against PARP1.

  • YN320879 Ziprasidone 146939-27-7

    Ziprasidone, an antipsychotic agent, is a combined5-HT (serotonin) and dopamine receptorantagonist. Ziprasidone has high affinity for rat (Ki: 3.4nM)/human (2.5nM) 5-HT1A receptors, 5-HT2A (0.42nM), and dopamine D2 receptor...

  • YN310336 Nicotinamide 98-92-0

    Nicotinamide (Vitamin B3), a water-soluble vitamin, is an active component of coenzymes NAD and NADP, and also act as an inhibitor of sirtuins.

  • YN350047 Pluripotin 839707-37-8

    Pluripotin (SC1) is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP with Kd values of 98 nM and 212 nM respectively. It maintains embryonic stem cell (ESC) self-renewal.

  • YN373130 Wedelolactone 524-12-9

    Wedelolactone inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.

  • YN330001 Peretinoin 81485-25-8

    Peretinoin is an oral acyclic retinoid retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such asretinoid X receptor(RXR) and retinoic acid receptor (RAR).

  • YN320539 BX471 217645-70-0

    BX471 (ZK-811752) is an orally active, potent and selective non-peptideCCR1antagonist with a Ki of 1nM, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.

  • YN320981 RS 504393 300816-15-3

    RS 504393 is a selectiveCCR2chemokine receptor antagonist (IC50 values are 89nM and > 100μM for inhibition of human recombinant CCR2 and CCR1 receptors respectively).

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