YN310005 ME0328 1445251-22-8

ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.

YN320358 (Z)-Thiothixene 3313-26-6

N/A

YN321657 Serotonin hydrochloride 153-98-0

Serotonin HCl is a monoamine neurotransmitter and Endogenous 5-HT receptor agonist.

YN360684 GSK1016790A 942206-85-1

GSK1016790A is a potent and selectivetransient receptor potential vanilloid 4 (TRPV4)channel agonist. GSK1016790A can elicit Ca2+influx and elevate intracellular Ca2+in HEK cells.

YN320455 Syk Inhibitor II 726695-51-8

Syk Inhibitor II is a potent, high selective and ATP-competitiveSykinhibitor with an IC50 of 41nM. Syk Inhibitor II inhibits5-HTrelease from RBL-cells with an IC50 of 460nM. Syk Inhibitor II shows less potent ag...

YN321265 Xanthotoxol 2009-24-7

Xanthotoxol is a biologically active linear furocoumarin, shows strong pharmacological activities as anti-inflammatory, antioxidant, 5-HT antagonistic, and neuroprotective effects.

YN251526 Coptisine chloride 6020-18-4

Coptisine chloride is an alkaloid from Chinese goldthread, and acts as an efficient uncompetitiveIDOinhibitor with aKivalue of 5.8μM and an IC50 value of 6.3μM. Coptisine chloride is a potentH1N1 neuraminidase (NA-1)inh...

YN321589 Thioridazine hydrochloride 130-61-0

Thioridazine is a potent antianxiety and antipsychotic agent.

YN350169 PF-4708671 1255517-76-0

PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) with Ki/IC50 of 20 nM/160 nM in cell-free assays, 400-fold greater selectivity for S6K1 than S6K2, and 4- and >20-fold selectivity for S6K1 t...