YN350155 Binimetinib 606143-89-9

Binimetinib (MEK162, ARRY-162, ARRY-438162) is a potent inhibitor of MEK1/2 with IC50 of 12 nM in a cell-free assay. Phase 3.

YN321302 CCG-63802 620112-78-9

CCG-63802 is a reversible inhibitor of regulator of G-protein signaling (RGS) protein; with greatest potency at RGS4. CCG-63802 is selective amongst RGS proteins, with greatest potency at RGS4. CCG-63802 inhibits GTP...

YN330058 Rapamycin 53123-88-9

Rapamycin (Sirolimus) is a specific mTOR inhibitor with IC50 of ~0.1 nM HEK293 cells.

YN330441 Mefenamic acid 61-68-7

Mefenamic Acid is a competitive inhibitor of COX-1 and COX-2.

YN373163 Schisandrin A 61281-38-7

Schisandrin A (Sch A) is an active component of Schisandrae Fructus with liver-protective, antitumor, and antioxidant activities. It is an agonist of the adiponectin receptor 2 (AdipoR2) with the IC50 value of 3.5 μM.

YN330407 Sodium Salicylate 54-21-7

Sodium salicylate is used in medicine as an analgesic and antipyretic.

YN330406 Salicylic acid 69-72-7

Salicylic acid is a beta hydroxy acid that occurs as a natural compound in plants which is an inhibitor of ethylene biosynthesis and cyclooxygenase activity.

YN330400 Sulindac 38194-50-2

Sulindac is a non-steroidal COX inhibitor, which potently inhibits prostaglandin synthesis, used in the treatment of acute or chronic inflammatory conditions.

YN251460 Cordycepin 73-03-0

Cordycepin is an adenosine analogue, which is readily phosphorylated to its mono-, di-, and triphosphate intracellularly. It has a very potent anti-cancer, anti-oxidant and anti-inflammatory activities.

YN370232 Tanespimycin 75747-14-7

Tanespimycin (17-AAG) is a potent HSP90 inhibitor with IC50 of 5 nM in a cell-free assay, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells. Phase 2.

YN320317 (+)-Cloprostenol 54276-21-0

(+)-Cloprostenol is a prostagl and in F2α (PGF2α) analogue, and shows selective agonistic activity at theprostagl and in receptor.