SCH-23390 hydrochloride
Cat. No. :YN321229
CAS No. :125941-87-9
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Product Name: | SCH-23390 hydrochloride |
CAS NO.: | 125941-87-9 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 324.24 |
Molecular Formula: | C₁₇H₁₉Cl₂NO |
SMILES: | OC1=C(Cl)C=C2CCN(C)C[C@H](C3=CC=CC=C3)C2=C1.[H]Cl |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | SCH-23390 hydrochloride (R-(+)-SCH-23390 hydrochloride) is a potent and selectivedopamine D1-like receptorantagonist with Kis of 0.2nM and 0.3nM for theD1 and D5receptor, respectively. SCH-23390 hydrochloride is a potent and high efficacyhuman 5-HT2Creceptoragonist with a Ki of 9.3nM. SCH-23390 hydrochloride also binds with high affinity to the5-HT2 and 5-HT1Creceptors. SCH-23390 hydrochloride inhibitsG protein-coupled inwardly rectifying potassium (GIRK) channelswith an IC50 of 268nM . |
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