YN340135 AG-1478

AG-1478 (Tyrphostin AG-1478) is a selective EGFR inhibitor with IC50 of 3 nM in cell-free assays, almost no activity on HER2-Neu, PDGFR, Trk, Bcr-Abl and InsR.

YN340125 EMI48 34564-13-1

EMI48, the derivative of EMI1, displays greater potency toward mutantEGFRthan EMI1. EMI48 inhibitsEGFRtriple mutants.

YN340247 Mutated EGFR-IN-1 1421372-66-8

Mutated EGFR-IN-1 (Osimertinib analog) is a useful intermediate for the inhibitors design for mutatedEGFR, such as L858R EGFR, Exonl9 deletion activating mutant and T790M resistance mutant. More information can be fo...

YN340155 Mutant EGFR inhibitor 1421373-62-7

Mutant EGFR inhibitor is a potent and selective mutantEGFRinhibitor extracted from patent WO 2013014448 A1; inhibits EGFRL858R, EGFRExon 19 deletion and EGFRT790M.

YN340046 AV-412 free base 451492-95-8

AV-412 free base (MP-412 free base) is an EGFRinhibitor with IC50s of 0.75, 0.5, 0.79, 2.3, 19nM for EGFR, EGFRL858R, EGFRT790M, EGFRL858R/T790M and ErbB2, respectively.

YN340045 AV-412 451493-31-5

AV-412 (MP412) is anEGFRinhibitor with IC50s of 0.75, 0.5, 0.79, 2.3, 19nM for EGFR, EGFRL858R, EGFRT790M, EGFRL858R/T790M and ErbB2, respectively.

YN340135 AG-1478 153436-53-4

AG-1478 (Tyrphostin AG-1478) is a selective EGFR inhibitor with IC50 of 3 nM in cell-free assays, almost no activity on HER2-Neu, PDGFR, Trk, Bcr-Abl and InsR.

YN320882 Quetiapine 111974-69-7

Quetiapine is an atypical antipsychotic used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder.

YN320426 Asenapine maleate 85650-56-2

Asenapine maleate is a high-affinity antagonist of serotonin, norepinephrine, dopamine and histamine receptors, used for the treatment of schizophrenia and acute mania associated with?bipolar disorder.

YN321229 SCH-23390 hydrochloride 125941-87-9

SCH-23390 hydrochloride (R-(+)-SCH-23390 hydrochloride) is a potent and selectivedopamine D1-like receptorantagonist with Kis of 0.2nM and 0.3nM for theD1 and D5receptor, respectively. SCH-23390 hydrochloride is a potent...

YN320881 Sertindole 106516-24-9

Sertindole, a neuroleptic, is one of the newer antipsychotic medications available.

YN330610 Pterosin B 34175-96-7

Pterosin B, a indanone found in bracken fern (Pteridium aquilinum), is an inhibitor ofsalt-inducible kinase 3 (Sik3)signaling. Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.

YN321711 Puerarin 3681-99-0

Puerarin (Kakonein), an isoflavones found in the root of Radix puerariae, is a 5-HT2C receptor and benzodiazepine site antagonist.

YN321065 Treprostinil sodium 289480-64-4

Treprostinil sodium (UT-15, Remodulin, Orenitram, Tyvaso, Trevyent) is a potent agonist of DP1, EP2 and IP receptors with Ki 4.4 nM, 3.6 nM and 32 nM, respectively.

YN321624 Terfenadine 50679-08-8

Terfenadine is an antihistamine, generally completely metabolizes to the active form fexofenadine in the liver by the enzyme cytochrome P450 CYP3A4 isoform.