YN380023 Phenserine 101246-66-6

Phenserine ((-)-Eseroline phenylcarbamate) is a derivative of Physostigmine and is a potent, noncompetitive, long-acting and selectiveAChEinhibitor. Phenserine reducesβ-amyloid precursor protein (APP) and β-amyloid peptide (...

YN380120 (-)-Huperzine A 102518-79-6

(-)-Huperzine A is a potent, highly specific and reversible inhibitor of acetylcholinesterase (AChE) with Ki of 7 nM, exhibiting 200-fold more selectivity for G4 AChE over G1 AChE. Also acts as an NMDA receptor antagonis...

YN380244 Huperzine B 103548-82-9

Huperzine-B is a efficient inhibitor of human brain AChE. Huperzine-B can enhance ognitive and protect neuro, may be potentially new drug candidates for Alzheimer's disease therapy.

YN380115 (+)-Phenserine 116839-68-0

(+)-Phenserine is a novel selectivecholinesterasenoncompetitive inhibitor with an IC50 of 45.3μM.

YN380155 Donepezil Hydrochloride 120011-70-3

Donepezil is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM , respectively.

YN380073 Dihydro Donepezil 120012-04-6

Dihydro Donepezil (Dihydro E2020) is a metabolite of Donepezil. Donepezil is a specific and potentAChEinhibitor with IC50s of 8.12nM and 11.6nM forbAChE and hAChE, respectively.

YN380101 Donepezil 120014-06-4

Donepezil is a piperidine based, potent, specific, non-competitive and reversible inhibitor of acetylcholinesterase (AChE) used for the treatment of mild to moderate dementia of the Alzheimer's type.

YN380121 (±)-Huperzine A 120786-18-7

(±)-Huperzine A, an active Lycopodium alkaloid extracted from traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheim...

YN380182 Itopride hydrochloride 122892-31-3

Itopride hydrochloride is an AChE inhibitor. The IC50 of itopride with AChE is 2.04 +/- 0.27 μM.

YN380119 Rivastigmine 123441-03-2

Rivastigmine is a cholinesterase inhibitor with IC50 of 5.5 μM. It inhibits acetylcholinesterase (IC50 = 4.15 ?M) and butyrylcholinesterase (IC50 = 37 nM).

YN380039 Rivastigmine tartrate 129101-54-8

Rivastigmine Tartrate is a cholinesterase inhibitor with IC50 of 5.5 μM, and used as a parasympathomimetic or cholinergic agent for the treatment of mild to moderate Alzheimer disease.

YN380273 Galanthamine N-Oxide 134332-50-6

Galanthamine N-Oxide is an alkaloid obtained from the bulbs ofZephyranthes concolor. Galanthamine N-Oxide inhibits electric eelacetylcholinesterase (AChE)with an EC50 of 26.2μM. Galanthamine N-Oxide is a prominent inhibitor...

YN380059 Huperzine C 163089-71-2

Huperzine C is an alkaloid isolated fromHuperzia serrate. Huperzine C is anacetylcholinesterase (AChE)inhibotor, with an IC50 of 0.6μM. Huperzine C can be used for the research of Alzheimer’s Disease.

YN380009 RPR121056 181467-56-1

RPR121056 (APC) is a metabolite of Irinotecan (CPT-11), which is generated by CYP3A4. Irinotecan (CPT-11) is an antineoplastic agent that inhibitstopoisomerase type I, causing cell death, and is widely used in the treat...

YN380263 Picfeltarraenin IV 184288-35-5

Picfeltarraenin IV, a triterpenoid obtained fromPicriafel-terraeLour (P.fel-terrae), is an acetylcholinesterase (AChE) inhibitor. Picfeltarraenin IV can be used for the treatment of herpes infections, cancer and inflammation.

YN380040 (R)-Rivastigmine D6 tartrat... 194930-00-2

(R)-Rivastigmine D6 tartrate is the deuterium labeled (R)-Rivastigmine, which is an cholinesterase inhibitor.

YN380213 Tacrine hydrochloride hydrate 206658-92-6

Tacrine is a centerally active cholinesterase inhibitor that has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders. It...

YN380024 Ladostigil 209394-27-4

Ladostigil (TV-3326) is a dual inhibitor ofcholinesterase and brain-selectivemonoamine oxidase (MAO), with an IC50 of 37.1 and 31.8μM forMAO-B and AChE, reapectively. Ladostigil could increase cholinergic transmission, ...

YN380212 Acotiamide monohydrochloride ... 773092-05-0

Acotiamide Hydrochloride is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. It is a new orally active selective acetylcholinesterase inhibitor.

YN380077 Rivastigmine carbamate impuri... 1346242-31-6

Rivastigmine carbamate impurity (3-Nitrophenyl ethyl(methyl)carbamate) is an impurity of Rivastigmine. Rivastigmine is an orally active and potent cholinesterase (ChE) inhibitor and inhibits butyrylcholinesterase (BChE) and a...