Apoptolidin
Cat. No. :YN360368
CAS No. :194874-06-1
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order@ubiochem.com| Product Name: | Apoptolidin |
| CAS NO.: | 194874-06-1 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 1129.37 |
| Molecular Formula: | C₅₈H₉₆O₂₁ |
| SMILES: | O[C@H]([C@](OC(/C(C)=C/C(C)=C/C(C)=C/[C@H]1C)=O)([H])C[C@@H]([C@H](CC/C=C(/C=C/[C@H]1O[C@H](O[C@H]2C)[C@H]([C@@H]([C@H]2OC)O)O)C)O)OC)[C@](O[C@@H]([C@@H]3C)C[C@H](COC)O[C@H](O[C@H]4C)C[C@](O)([C@H]4O[C@H](O[C@@H]5C)C[C@H]([C@@H]5O)OC)C)([C@@H]([C@H]3O)C)O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Apoptolidin is a polyketide isolated fromNocardiopsisbacteria. Apoptolidin is a selective mitochondrialF1FOATPaseinhibitor. Apoptolidin is an apoptosis inducer and induces apoptotic cell death in cells transformed with the adenovirus type 12 oncogenes including ElA (IC50=10-17 ng/ml) but not in normal cells. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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