Semagacestat
Cat. No. :YN380002
CAS No. :425386-60-3
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order@ubiochem.com| Product Name: | Semagacestat |
| CAS NO.: | 425386-60-3 |
| Chemical Name: | |
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| Molecular Weight: | 361.44 |
| Molecular Formula: | C₁₉H₂₇N₃O₄ |
| SMILES: | O=C([C@H]1NC([C@@H](NC([C@H](C(C)C)O)=O)C)=O)N(CCC2=C1C=CC=C2)C |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Semagacestat (LY450139) is a γ-secretase blocker for Aβ42, Aβ40 and Aβ38 with IC50 of 10.9 nM, 12.1 nM and 12.0 nM, also inhibits Notch signaling with IC50 of 14.1 nM in H4 human glioma cell. Phase 3. |
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