ARN2966
Cat. No. :YN380129
CAS No. :102212-26-0
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order@ubiochem.com| Product Name: | ARN2966 |
| CAS NO.: | 102212-26-0 |
| Chemical Name: | |
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| Molecular Weight: | 200.24 |
| Molecular Formula: | C₁₂H₁₂N₂O |
| SMILES: | OC1=CC=CC=C1NCC2=NC=CC=C2 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | ARN2966 is a potent post-transcriptional modulator of APP expression; reduces expression of APP with resultant lower production of Aβ. This potent post-transcriptional modulation of APP expression differs from other mechanisms such as inhibition of secretases. Secretase inhibitors have been pursued as disease modifying strategies by a number of pharmaceutical firms but they have encountered numerous setbacks during clinical development. ARN2966 is non toxic, orally absorbable, blood-brain-barrier penetrable, and effective in vitro and in vivo. |
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