Dihydroergocristine mesylate
Cat. No. :YN380251
CAS No. :24730-10-7
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Product Name: | Dihydroergocristine mesylate |
CAS NO.: | 24730-10-7 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 707.84 |
Molecular Formula: | C₃₆H₄₅N₅O₈S |
SMILES: | O[C@@]([C@@](CCC1)([H])N1C2=O)(O[C@](NC([C@@H](CN(C)[C@]3([H])C4)C[C@]3([H])C5=C6C4=CNC6=CC=C5)=O)(C(C)C)C7=O)N7[C@H]2CC8=CC=CC=C8.CS(=O)(O)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Dihydroergocristine mesylate (DHEC mesylate) is a inhibitor of γ-secretase (GSI), reduces the production of the Alzheimer's diseaseamyloid-βpeptides, binds directly to γ-secretase and Nicastrin with equilibrium dissociation constants (Kd) of 25.7nM and 9.8μM, respectively. |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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