YN250867 Tunicamycin 11089-65-9

Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibitsN-linked glycosylation and blocksGlcNAc phosphotransferase (GPT). Tunicamycin causes accumulation of unfolded proteins in cell endoplasmic reticulum (ER) ...

YN250975 Rifampicin 13292-46-1

Rifampin is a DNA-dependent RNA polymerase inhibitor, used to treat a number of bacterial infections.

YN250712 Minocycline hydrochloride 13614-98-7

Minocycline HCl is the most lipid soluble and most active tetracycline antibiotic, binds to the 30S ribosomal subunit, preventing the binding of tRNA to the mRNA-ribosome complex and interfering with protein synthesis.

YN250870 Plicamycin 18378-89-7

Plicamycin is a selective specificity protein 1 (Sp1) inhibitor. Plicamycin inhibits the growth of various cancers by decreasing Sp1 protein.

YN250563 Streptozocin 18883-66-4

Streptozotocin is a glucosamine-nitrosourea derivative, which is a methylating, carcinogenic, antibiotic and diabetes inducing agent.

YN250671 Brefeldin A 20350-15-6

Brefeldin A is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells, induces cancer cell differentiation and apoptosis.

YN251042 Spectinomycin dihydrochloride 21736-83-4

Spectinomycin 2HCl is a new parenteral antibiotic prepared from Streptomyces spectabilis.

YN250443 Daunorubicin Hydrochloride 23541-50-6

Daunorubicin HCl inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM in a cell-free assay.

YN250620 Doxorubicin hydrochloride 25316-40-9

Doxorubicin (Adriamycin) HCl is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis in tumor cells.

YN250669 Kanamycin sulfate 25389-94-0

Kanamycin sulfate(Kanamycin monosulfate) is an aminoglycoside antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections.

YN251066 Hygromycin B 31282-04-9

Hygromycin B, a selective antibiotic that is effective on most bacteria, fungi and higher eukaryotes, inhibits protein synthesis by interfering with translocation and causing mistranslation at the 70S ribosome.

YN250522 Etoposide 33419-42-0

Etoposide is a semisynthetic derivative of podophyllotoxin, which inhibits DNA synthesis via topoisomerase II inhibition activity.

YN251717 Myriocin 35891-70-4

Myriocin, a fungal metabolite isolated fromMyriococcum albomyces,Isaria sinclairi and Mycelia sterilia, is a potent inhibitor ofserine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids. Myriocin str...

YN251040 Ribavirin 36791-04-5

Ribavirin, a synthetic guanosine analogue, possesses a broad spectrum of activity against DNA and RNA viruses.

YN251034 Fenbendazole 43210-67-9

Fenbendazole is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites with an IC50 of about 0.01 μg/mL.

YN251685 Calcimycin 52665-69-7

Calcimycin (A-23187) is an antibiotic and a uniquedivalent cation ionophore(like calcium and magnesium). Calcimycin induces Ca2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin inhibits the growth...

YN250645 Salinomycin 53003-10-4

Salinomycin (Procoxacin), a polyether potassium ionophore antibiotic, selectively inhibits the growth ofgram-positive bacteria. Salinomycin is a potent inhibitor ofWnt/β-cateninsignaling, blocks Wnt-induced LRP6 phosphorylation. S...

YN250959 Albendazole 54965-21-8

Albendazole is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations.

YN250077 Sinefungin 58944-73-3

Sinefungin is a potent inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication. Sinefungin, aSET7/9inhibitor, ameliorates renal fibrosis by inhibiting H3K4 meth...

YN250751 Bleomycin hydrochloride 67763-87-5

Bleomycin hydrochloride is a DNA synthesisinhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin hydrochloride is an antitumor antibiotic.