Zamicastat
Cat. No. :YN360162
CAS No. :1080028-80-3
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order@ubiochem.com| Product Name: | Zamicastat |
| CAS NO.: | 1080028-80-3 |
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| Molecular Weight: | 401.47 |
| Molecular Formula: | C₂₁H₂₁F₂N₃OS |
| SMILES: | S=C1N([C@@H]2CC3=CC(F)=CC(F)=C3OC2)C(CCNCC4=CC=CC=C4)=CN1 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Zamicastat (BIA 5-1058) is adopamine β-hydroxylase (DBH)inhibitor and can cross the blood-brain barrier (BBB) to cause central as well as peripheral effects. Zamicastat is also a concentration-dependent dualP-gp and BCRPinhibitor with IC50 values of 73.8 μM and 17.0 μM, respectively. Zamicastat reduces high blood pressure. |
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