BMX-IN-1
Cat. No. :YN440416
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5mg
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10mg
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25mg
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Product Name: | BMX-IN-1 |
CAS NO.: | 1431525-23-3 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 524.59 |
Molecular Formula: | C₂₉H₂₄N₄O₄S |
SMILES: | O=C1N(C2=C(C=C1)C=NC3=CC=C(C4=CC=C(NS(=O)(C)=O)C=C4)C=C32)C5=CC=C(C)C(NC(C=C)=O)=C5 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | BMX-IN-1 is a selective, irreversible inhibitor ofbone marrow tyrosine kinase on chromosome X (BMX)that targets Cys496in the BMX ATP binding domain with an IC50 of 8nM, also targets the related Bruton’s tyrosine kinase(BTK)with an IC50 value of 10.4nM, but is more than 47-656-fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity. |
IC50&Target: | |
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References: |
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