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BMX-IN-1

Cat. No. :YN440416

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    • Products Infomation
    • Biological Activity
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    • Product Name:BMX-IN-1
      CAS NO.:1431525-23-3
      Chemical Name:
      Synonyms:
      Molecular Weight:524.59
      Molecular Formula:C₂₉H₂₄N₄O₄S
      SMILES:O=C1N(C2=C(C=C1)C=NC3=CC=C(C4=CC=C(NS(=O)(C)=O)C=C4)C=C32)C5=CC=C(C)C(NC(C=C)=O)=C5
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:BMX-IN-1 is a selective, irreversible inhibitor ofbone marrow tyrosine kinase on chromosome X (BMX)that targets Cys496in the BMX ATP binding domain with an IC50 of 8nM, also targets the related Bruton’s tyrosine kinase(BTK)with an IC50 value of 10.4nM, but is more than 47-656-fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity.
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