c-di-AMP
Cat. No. :YN250335
CAS No. :54447-84-6
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Product Name: | c-di-AMP |
CAS NO.: | 54447-84-6 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 658.41 |
Molecular Formula: | C₂₀H₂₄N₁₀O₁₂P₂ |
SMILES: | O[C@H]([C@@](OP(O)(OC[C@](O[C@@H](N1C2=NC=NC(N)=C2N=C1)[C@@H]3O)([H])[C@@]3([H])O4)=O)([H])[C@](COP4(O)=O)([H])O5)[C@@H]5N6C7=NC=NC(N)=C7N=C6 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | c-di-AMP (Cyclic diadenylate) is aSTINGagonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP (Cyclic diadenylate) is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP (Cyclic diadenylate) acts as a potent mucosal adjuvant stimulating both humoral and cellular responses. |
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References: |
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