Calcimycin hemicalcium salt
Cat. No. :YN251686
CAS No. :59450-89-4
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Product Name: | Calcimycin hemicalcium salt |
CAS NO.: | 59450-89-4 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 1085.30 |
Molecular Formula: | C₅₈H₇₂CaN₆O₁₂ |
SMILES: | CNC1=CC=C2OC(C[C@@H]3[C@@H](CC[C@@]4(O3)[C@@H](C[C@H]([C@H](O4)[C@@H](C(C5=CC=CN5)=O)C)C)C)C)=NC2=C1C([O-][Ca+2][O-]C(C6=C7N=C(C[C@H]8O[C@]9(O[C@H]([C@H](C)C(C%10=CC=CN%10)=O)[C@H](C)C[C@H]9C)CC[C@H]8C)OC7=CC=C6NC)=O)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Calcimycin hemicalcium salt (A-23187 hemicalcium salt) is an antibiotic and a uniquedivalent cation ionophore(like calcium and magnesium). Calcimycin hemicalcium salt induces Ca2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin hemicalcium salt inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin hemicalcium salt also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin hemicalcium salt inducesapoptosis. |
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References: |
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