Framycetin
Cat. No. :YN250774
CAS No. :119-04-0
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order@ubiochem.com| Product Name: | Framycetin |
| CAS NO.: | 119-04-0 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 614.64 |
| Molecular Formula: | C₂₃H₄₆N₆O₁₃ |
| SMILES: | N[C@@H](C[C@H]1N)[C@@]([C@@H]([C@H]1O)O[C@@](O[C@H](CO)[C@H]2O[C@@]([C@@H]([C@@H](O)[C@@H]3O)N)([H])O[C@H]3CN)([H])[C@@H]2O)([H])O[C@H]([C@@H]([C@@H](O)[C@@H]4O)N)O[C@@H]4CN |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Framycetin (Neomycin B), an aminoglycoside antibiotic, is a potentRNase P cleavage activityinhibitor with a Ki of 35μM. Framycetin competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin inhibitshammerhead ribozymewith a Ki of 13.5μM. Framycetin, a 5″-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenicE. coliinfections. |
| IC50&Target: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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