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Actinonin

Cat. No. :YN250231

  • CAS No. :13434-13-4

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    • Products Infomation
    • Biological Activity
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    • Product Name:Actinonin
      CAS NO.:13434-13-4
      Chemical Name:
      Synonyms:
      Molecular Weight:385.50
      Molecular Formula:C₁₉H₃₅N₃O₅
      SMILES:O=C(N[C@H](C(N1[C@H](CO)CCC1)=O)C(C)C)[C@H](CCCCC)CC(NO)=O
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced byActinomyces. Actinonin inhibitsaminopeptidase M,aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversiblepeptide deformylase (PDF)inhibitor with a Ki of 0.28nM. Actinonin also inhibitsMMP-1,MMP-3,MMP-8,MMP-9, and hmeprin αwith Ki values of 300nM, 1,700nM, 190nM, 330nM, and 20nM, respectively. Actinonin is anapoptosisinducer. Actinonin has antiproliferative and antitumor activities .
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