Actinonin
Cat. No. :YN250231
CAS No. :13434-13-4
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Product Name: | Actinonin |
CAS NO.: | 13434-13-4 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 385.50 |
Molecular Formula: | C₁₉H₃₅N₃O₅ |
SMILES: | O=C(N[C@H](C(N1[C@H](CO)CCC1)=O)C(C)C)[C@H](CCCCC)CC(NO)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced byActinomyces. Actinonin inhibitsaminopeptidase M,aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversiblepeptide deformylase (PDF)inhibitor with a Ki of 0.28nM. Actinonin also inhibitsMMP-1,MMP-3,MMP-8,MMP-9, and hmeprin αwith Ki values of 300nM, 1,700nM, 190nM, 330nM, and 20nM, respectively. Actinonin is anapoptosisinducer. Actinonin has antiproliferative and antitumor activities . |
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References: |
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