Rifalazil
Cat. No. :YN250110
CAS No. :129791-92-0
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order@ubiochem.com| Product Name: | Rifalazil |
| CAS NO.: | 129791-92-0 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 941.07 |
| Molecular Formula: | C₅₁H₆₄N₄O₁₃ |
| SMILES: | CC(C)CN(CC1)CCN1C2=CC(O3)=C(C(O)=C2)N=C(C3=C(NC(/C(C)=CC=C[C@@H]([C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@@H]([C@@H]([C@H](/C=C/O[C@@]4(C)O5)OC)C)OC(C)=O)C)=O)C6=O)C7=C6C(O)=C(C)C5=C7C4=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Rifalazil (KRM-1648; ABI-1648), a rifamycin derivative, inhibits the bacterial DNA-dependentRNA polymerase and kills bacterial cells by blocking off the β-subunit in RNA polymerase. Rifalazil (KRM-1648; ABI-1648) is anantibiotic, exhibits high potency against mycobacteria, gram-positive bacteria,Helicobacter pylori,C. pneumoniae and C. trachomatiswithMICvalues from 0.00025 to 0.0025 μg/ml. Rifalazil (KRM-1648; ABI-1648) has the potential for the treatment of Chlamydia infection, Clostridium difficile associated diarrhea (CDAD), and tuberculosis (TB). |
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| References: |
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