Dictamine
Cat. No. :YN251540
CAS No. :484-29-7
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5mg
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Product Name: | Dictamine |
CAS NO.: | 484-29-7 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 199.21 |
Molecular Formula: | C₁₂H₉NO₂ |
SMILES: | COC1=C2C(OC=C2)=NC3=CC=CC=C13 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Dictamnine (Dictamine) has the ability to exert cytotoxicity in human cervix, colon, and oral carcinoma cells; A natural plant product has been reported to have antimicrobial activity against bacteria and fungi. Dictamnine has antimicrobial activities against the model fungus Saccharomyces cerevisiae, with a minimum inhibitory concentration (MIC) value of 64 microg/ml . Dic induced S phase cell cycle arrest at low concentration and cell apoptosis at high concentration in which loss of mitochondrial membrane potential (Δψmm) was not involved. In addition, inhibition of caspase-3 using the specific inhibitor, z-DQMD-fmk, did not attenuate Dic-induced apoptosis, implying that Dic-induced caspase-3-independent apoptosis . |
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