Trovafloxacin mesylate
Cat. No. :YN250092
CAS No. :147059-75-4
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Product Name: | Trovafloxacin mesylate |
CAS NO.: | 147059-75-4 |
Chemical Name: | |
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Molecular Weight: | 512.46 |
Molecular Formula: | C₂₁H₁₉F₃N₄O₆S |
SMILES: | O=C(C1=CN(C2=CC=C(F)C=C2F)C3=NC(N4C[C@@]5([H])[C@H](N)[C@@]5([H])C4)=C(F)C=C3C1=O)O.CS(=O)(O)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Trovafloxacin mesylate is a broad-spectrum quinolone antibiotic with potent activity againstGram-positive,Gram-negative and anaerobic organisms. Trovafloxacin mesylate blocks theDNA gyrase and topoisomerase IVactivity. Trovafloxacin mesylate is also a potent, selective and orally activepannexin 1 channel (PANX1)inhibitor with an IC50 of 4μM forPANX1inward current. Trovafloxacin mesylate does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin mesylate leads to dysregulated fragmentation of apoptotic cells by inhibitingPANX1 . |
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