N-Acetyl-D-mannosamine
Cat. No. :YN250419
CAS No. :3615-17-6
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order@ubiochem.com| Product Name: | N-Acetyl-D-mannosamine |
| CAS NO.: | 3615-17-6 |
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| Molecular Weight: | 221.21 |
| Molecular Formula: | C₈H₁₅NO₆ |
| SMILES: | OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](C=O)NC(C)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | N-Acetyl-D-mannosamine (ManNAc) is an essential precursor of N-acetylneuraminic acid (NeuAc), the specific monomer of bacterial capsular polysialic acid (PA). N-Acetyl-D-mannosamine (ManNAc) can be metabolized by GNE and GlcNAc 2-epimerase (Renin binding protein, RnBP), into ManNAc-6-phosphate and GlcNAc, respectively. N-Acetyl-d-mannosamine (ManNAc) and its derivatives activates hypocretin (HCRT) gene expression in the orexin neurons, providing a potential model for the testing of a therapy for neural disorders. |
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