NITD-916
Cat. No. :YN250327
CAS No. :1614262-83-7
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order@ubiochem.com| Product Name: | NITD-916 |
| CAS NO.: | 1614262-83-7 |
| Chemical Name: | |
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| Molecular Weight: | 311.42 |
| Molecular Formula: | C₂₀H₂₅NO₂ |
| SMILES: | O=C1C(C2=CC=CC=C2)=C(O)C=C(CC3CCC(C)(C)CC3)N1 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | NITD-916, a 4-hydroxy-2-pyridone derivative, is an orally active and highly lipophilicmycobacterial enoyl reductase InhAinhibitor with an IC50 of 570nM. NITD-916 forms a ternary complex withInhA and NADH to block access to the fatty acyl substrate binding pocket. NITD-916 has potent anti-tuberculosis effects. |
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