PD176252
Cat. No. :YN320252
CAS No. :204067-01-6
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order@ubiochem.com| Product Name: | PD176252 |
| CAS NO.: | 204067-01-6 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 584.67 |
| Molecular Formula: | C₃₂H₃₆N₆O₅ |
| SMILES: | O=C(NC1=CC=C([N+]([O-])=O)C=C1)N[C@](CC2=CNC3=C2C=CC=C3)(C)C(NCC4(C5=CC=C(OC)C=N5)CCCCC4)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | PD176252 is a potent antagonist of neuromedin-B preferring (BB1) and gastrin-releasing peptide-preferring (BB2) receptor with Kis of 0.17nM and 1nM for human BB1 and BB2receptors, and 0.66nM, 16nM for Rat BB1 and BB2receptors, respectively; PD176252 is also an agonist of N-Formyl peptide receptor1/2 (FPR1/FPR2), with EC50s of 0.31 and 0.66μM in HL-60 cells. |
| IC50&Target: | |
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| Solvent & Solubility: | |
| References: |
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